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Ligand · LNV

LNV · 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid

LNV, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid (C13 H22 N4 O7, 346.3 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site…

Component
LNV
Formula
C13 H22 N4 O7
Class
sugar
Structures
14
PDB entries
7

Binding sites

LNV in 14 structures; the first of them:

  • 3TI3 · Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with laninamivir · LNV A801 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 3TI8 · Crystal structure of influenza A virus neuraminidase N5 complexed with laninamivir · LNV A901 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 12 more
  • 3TIA · Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir · LNV A801 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 4HZW · Crystal structure of influenza A neuraminidase N3 complexed with laninamivir · LNV A509 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 4MWU · Anhui N9-laninamivir · LNV A513 · binds ARG119, GLU120, LEU135, ASP152, ARG153, ARG157, TRP180, SER181 and 11 more
  • 4MWY · Shanghai N9-laninamivir · LNV A513 · binds ARG119, GLU120, LEU135, ASP152, ARG153, ARG157, TRP180, SER181 and 10 more
  • 4QN6 · Crystal structure of Neuraminidase N6 complexed with Laninamivir · LNV A511 · binds ARG39, GLU40, LEU55, ASP72, ARG73, ARG77, TRP100, SER101 and 11 more
  • 3TI3 · Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with laninamivir · LNV A801 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 3TI8 · Crystal structure of influenza a virus neuraminidase N5 complexed with laninamivir · LNV A901 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 12 more
  • 3TIA · Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir · LNV A801 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 4HZW · Crystal structure of influenza a neuraminidase N3 complexed with laninamivir · LNV A509 · binds ARG118, GLU119, LEU134, ASP151, ARG152, ARG156, TRP178, SER179 and 11 more
  • 4MWU · Anhui N9-laninamivir · LNV A513 · binds ARG119, GLU120, LEU135, ASP152, ARG153, ARG157, TRP180, SER181 and 11 more
  • 4MWY · Shanghai N9-laninamivir · LNV A513 · binds ARG119, GLU120, LEU135, ASP152, ARG153, ARG157, TRP180, SER181 and 10 more
  • 4QN6 · Crystal structure of neuraminidase N6 complexed with laninamivir · LNV A511 · binds ARG39, GLU40, LEU55, ASP72, ARG73, ARG77, TRP100, SER101 and 11 more

Residues it binds most

ARG 26, GLU 26, SER 26, TYR 26, ASN 26, ASP 26, ILE 26, LEU 26, TRP 26, GLY 24 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • FUC · alpha-L-fucopyranose
  • ACT · Acetate ion
  • GOL · Glycerol

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