GL1X · GenesisL1 explorer

Ligand · LLH

LLH · (2R,3S,4R)-2,3,4-trihydroxy-5-(hydroxyamino)-5-oxopentanoic acid

LLH, (2R,3S,4R)-2,3,4-trihydroxy-5-(hydroxyamino)-5-oxopentanoic acid (C5 H9 N O7, 195.1 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
LLH
Formula
C5 H9 N O7
Class
ligand
Structures
6
PDB entries
3

Binding sites

LLH in 6 structures; the first of them:

  • 2PP1 · Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2… · LLH A801 · binds VAL44, ASP46, LYS48, LEU57, LYS82, ARG83, THR167, PHE171 and 10 more
  • 4HCL · CRYSTAL STRUCTURE OF D-GLUCARATE DEHYDRATASE FROM AGROBACTERIUM TUMEFACIENS complexed… · LLH A403 · binds GLY23, HIS24, CYS139, LYS169, HIS171, MET174, ASP206, HIS209 and 7 more
  • 4MMW · Crystal structure of D-glucarate dehydratase from Agrobacterium tumefaciens complexed… · LLH A405 · binds GLY23, HIS24, CYS139, LYS169, HIS171, MET174, ASP206, HIS209 and 7 more
  • 2PP1 · Crystal structure of L-TALARATE/GALACTARATE dehydratase from salmonella typhimurium LT2… · LLH A801 · binds VAL44, ASP46, LYS48, LEU57, LYS82, ARG83, THR167, PHE171 and 10 more
  • 4HCL · Crystal structure of D-glucarate dehydratase from agrobacterium tumefaciens complexed… · LLH A403 · binds GLY23, HIS24, CYS139, LYS169, HIS171, MET174, ASP206, HIS209 and 7 more
  • 4MMW · Crystal structure of D-glucarate dehydratase from agrobacterium tumefaciens complexed… · LLH A405 · binds GLY23, HIS24, CYS139, LYS169, HIS171, MET174, ASP206, HIS209 and 7 more

Residues it binds most

GLU 20, LYS 20, HIS 20, ASP 20, ARG 20, PHE 12, LEU 20, ASN 12, THR 12, TRP 12 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • XYH · Xylarohydroxamate
  • CL · Chloride ion
  • PG4 · Tetraethylene glycol
  • PGE · Triethylene glycol

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