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Ligand · L2G

L2G · N-(4-{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

L2G, N-(4-{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide (C34 H39 N9 O3, 621.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
L2G
Formula
C34 H39 N9 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

L2G in 2 structures; the first of them:

  • 2C0O · Src family kinase Hck with bound inhibitor A-770041 · L2G A1506 · binds LEU247, GLY248, VAL255, ALA267, VAL268, LYS269, PHE281, ALA285 and 18 more
  • 2C0O · Src family kinase hck with bound inhibitor a-770041 · L2G A1506 · binds LEU247, GLY248, VAL255, ALA267, VAL268, LYS269, PHE281, ALA285 and 18 more

Residues it binds most

LEU 4, GLY 4, PHE 4, VAL 4, ALA 4, ASP 4, ILE 4, MET 4, GLU 4, LYS 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion

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