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Ligand · L1G

L1G · N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

L1G, N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide (C33 H39 N9 O2, 593.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
L1G
Formula
C33 H39 N9 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

L1G in 2 structures; the first of them:

  • 2C0I · Src family kinase Hck with bound inhibitor A-420983 · L1G A1506 · binds LEU247, GLY248, VAL255, ALA267, VAL268, LYS269, PHE281, GLU284 and 19 more
  • 2C0I · Src family kinase hck with bound inhibitor a-420983 · L1G A1506 · binds LEU247, GLY248, VAL255, ALA267, VAL268, LYS269, PHE281, GLU284 and 19 more

Residues it binds most

LEU 4, ALA 4, GLY 4, PHE 4, VAL 4, ASP 4, MET 4, GLU 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion

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