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Ligand · KRJ

KRJ · 4-cyano-N-(2-cyclohex-1-en-1-yl-4-piperidin-4-ylphenyl)-1H-imidazole-2-carboxamide

KRJ, 4-cyano-N-(2-cyclohex-1-en-1-yl-4-piperidin-4-ylphenyl)-1H-imidazole-2-carboxamide (C22 H25 N5 O, 375.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
KRJ
Formula
C22 H25 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

KRJ in 2 structures; the first of them:

  • 3KRJ · cFMS tyrosine kinase in complex with 4-Cyano-1H-imidazole-2-carboxylic acid… · KRJ A923 · binds LEU588, VAL596, ALA614, LYS616, VAL647, THR663, GLU664, TYR665 and 10 more
  • 3KRJ · Cfms tyrosine kinase in complex with 4-cyano-1H-imidazole-2-carboxylic acid… · KRJ A923 · binds LEU588, VAL596, ALA614, LYS616, VAL647, THR663, GLU664, TYR665 and 10 more

Residues it binds most

ALA 2, ASP 2, CYS 2, LEU 2, TYR 2, VAL 2, ARG 2, GLU 2, GLY 2, LYS 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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