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Ligand · KRH

KRH · 5-methyl-3-(1-methyl-1H-imidazol-5-yl)-7-(2-methylpropyl)-2-(naphthalen-1-ylmethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

KRH, 5-methyl-3-(1-methyl-1H-imidazol-5-yl)-7-(2-methylpropyl)-2-(naphthalen-1-ylmethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione (C25 H26 N6 O2, 442.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
KRH
Formula
C25 H26 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

KRH in 2 structures; the first of them:

  • 4B1F · Design of Inhibitors of Helicobacter pylori Glutamate Racemase as Selective Antibacterial… · KRH A1256 · binds VAL10, GLY11, PHE13, SER14, LYS17, ILE149, GLU150, SER152 and 8 more
  • 4B1F · Design of inhibitors of helicobacter pylori glutamate racemase as selective antibacterial… · KRH A1256 · binds VAL10, GLY11, PHE13, SER14, LYS17, ILE149, GLU150, SER152 and 8 more

Residues it binds most

LEU 4, SER 4, TRP 4, GLN 4, GLU 4, GLY 4, HIS 4, ILE 4, LYS 4, PHE 4 (residue and the binding sites it lines).

Found with

  • DGL · D-glutamic acid

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