GL1X · GenesisL1 explorer

Ligand · KFR

KFR · methyl (2S)-2-[[(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-(4-oxidanylphenoxy)butanoyl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoate

KFR, methyl (2S)-2-[[(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-(4-oxidanylphenoxy)butanoyl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoate (C28 H36 N4 O7, 540.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
KFR
Formula
C28 H36 N4 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

KFR in 2 structures; the first of them:

  • 7ZYF · Insulin regulated aminopeptidase (IRAP) in complex with a nanomolar alpha hydroxy beta… · KFR A1106 · binds TYR272, GLN293, GLU295, PRO296, GLU426, ALA427, GLY428, ALA429 and 12 more
  • 7ZYF · Insulin regulated aminopeptidase (irap) in complex with a nanomolar alpha hydroxy beta… · KFR A1106 · binds GLN293, GLU295, PRO296, GLU426, ALA427, GLY428, ALA429, MET430 and 9 more

Residues it binds most

GLU 4, TYR 4, ALA 4, HIS 4, GLN 4, GLY 4, ILE 4, MET 4, PHE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.