GL1X · GenesisL1 explorer

Ligand · KFR

KFR · methyl (2S)-2-[[(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-(4-oxidanylphenoxy)butanoyl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoate

KFR, methyl (2S)-2-[[(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-(4-oxidanylphenoxy)butanoyl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoate (C28 H36 N4 O7, 540.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
KFR
Formula
C28 H36 N4 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

KFR in 2 structures; the first of them:

  • 7ZYF · Insulin regulated aminopeptidase (IRAP) in complex with a nanomolar alpha hydroxy beta… · KFR A1106 · binds TYR272, GLN293, GLU295, PRO296, GLU426, ALA427, GLY428, ALA429 and 12 more
  • 7ZYF · Insulin regulated aminopeptidase (irap) in complex with a nanomolar alpha hydroxy beta… · KFR A1106 · binds TYR272, GLN293, GLU295, PRO296, GLU426, ALA427, GLY428, ALA429 and 12 more

Residues it binds most

GLU 4, TYR 4, ALA 4, HIS 4, GLN 4, GLY 4, ILE 4, MET 4, PHE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.