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Ligand · KDK

KDK · 4-phenyl-5-(piperidin-4-ylmethyl)thiophene-2-carboximidamide

KDK, 4-phenyl-5-(piperidin-4-ylmethyl)thiophene-2-carboximidamide (C17 H21 N3 S, 299.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
KDK
Formula
C17 H21 N3 S
Class
ligand
Structures
2
PDB entries
2

Binding sites

KDK in 2 structures; the first of them:

  • 6RP6 · Fragment az-019 binding at the TAZPS89/14-3-3 sigma interface · KDK A301 · binds GLU14, GLU39, ASN42, LEU43, VAL46, ASP215, SER131
  • 6S3C · Fragment az-019 binding at the P53PT387/14-3-3 sigma interface · KDK A304 · binds GLU14, CYS38, GLU39, ASN42, LEU43, ASP215

Residues it binds most

GLU 2, ASN 2, ASP 2, LEU 2, CYS 1, SER 1, VAL 1 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • MG · Magnesium ion
  • NA · Sodium ion
  • CL · Chloride ion
  • GOL · Glycerol

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