Ligand · K9J
K9J · 1-{4-[2-{[(2R)-1-(dimethylamino)propan-2-yl]oxy}-7-(3-hydroxynaphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one
K9J, 1-{4-[2-{[(2R)-1-(dimethylamino)propan-2-yl]oxy}-7-(3-hydroxynaphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one (C29 H38 N6 O3, 518.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2…
- Component
- K9J
- Formula
- C29 H38 N6 O3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
K9J in 2 structures; the first of them:
- 6N2K · Tetrahydropyridopyrimidines as Covalent Inhibitors of KRAS-G12C · K9J A203 · binds GLY10, ALA11, CYS12, LYS16, PRO34, THR58, ALA59, GLY60 and 16 more
- 6N2K · Tetrahydropyridopyrimidines as covalent inhibitors of KRAS-G12C · K9J A203 · binds GLY10, ALA11, CYS12, LYS16, PRO34, THR58, ALA59, GLY60 and 15 more
Residues it binds most
ALA 2, ARG 2, ASP 2, GLU 2, GLY 2, LYS 2, TYR 2, GLN 2, CYS 2, HIS 2 (residue and the binding sites it lines).
Found with
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