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Ligand · K7N

K7N · 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide

K7N, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide (C16 H17 N5 S, 311.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
K7N
Formula
C16 H17 N5 S
Class
ligand
Structures
3
PDB entries
3

Binding sites

K7N in 3 structures; the first of them:

  • 6RL4 · Fragment az-025 binding at the P53PT387/14-3-3 sigma interface · K7N A304 · binds GLU14, CSO38, GLU39, ASN42, LEU43, VAL46, PRO167, ASP215
  • 7NND · Crystal structure of 14-3-3 sigma in complex with 13MER amot-P130 peptide and fragment 09 · K7N A303 · binds GLU14, CSO38, GLU39, ASN42, LEU43, VAL46, PRO167, MET179
  • 7NPB · Crystal structure of 14-3-3 sigma in complex with 20MER amot-P130 peptide and fragment 09 · K7N A301 · binds GLU14, CSO38, GLU39, ASN42, LEU43, VAL46, PRO167, MET179

Residues it binds most

GLU 3, ASN 3, CSO 3, LEU 3, PRO 3, VAL 3, MET 2, ASP 1 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • MG · Magnesium ion
  • CA · Calcium ion

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