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Ligand · JTT

JTT · 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide

JTT, 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide (C16 H14 N2 O S, 282.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
JTT
Formula
C16 H14 N2 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

JTT in 2 structures; the first of them:

  • 4JTT · Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 066 · JTT A409 · binds TYR38, LEU42, MET43, ALA59, PHE62, THR63, LEU67, LEU68 and 4 more
  • 4JTT · Crystal structure of human dihydroorotate dehydrogenase (dhodh) with 066 · JTT A409 · binds TYR38, LEU42, MET43, ALA59, PHE62, THR63, LEU67, LEU68 and 4 more

Residues it binds most

LEU 2, MET 2, PHE 2, PRO 2, ALA 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • ORO · Orotic acid
  • SO4 · Sulfate ion
  • ACT · Acetate ion

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