Ligand · JPZ
JPZ · quinazolin-4(1H)-one
JPZ, quinazolin-4(1H)-one (C8 H6 N2 O, 146.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- JPZ
- Formula
- C8 H6 N2 O
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
JPZ in 6 structures; the first of them:
- 3NUY · phosphoinositide-dependent kinase-1 (PDK1) with fragment17 · JPZ A370 · binds LEU88, VAL96, ALA109, VAL143, LEU159, SER160, TYR161, ALA162 and 3 more
- 4LM4 · Crystal structure of PDE10A2 with fragment ZT902 · JPZ A900 · binds TYR524, ASP674, LEU675, SER677, VAL678, ILE692, PHE696, GLN726 and 1 more
- 4PNN · Crystal Structure of human Tankyrase 2 in complex with 4HQN. · JPZ A1202 · binds PHE1030, HIS1031, GLY1032, TYR1060, PHE1061, ALA1062, LYS1067, SER1068 and 2 more
- 3NUY · Phosphoinositide-dependent kinase-1 (PDK1) with FRAGMENT17 · JPZ A370 · binds LEU88, VAL96, ALA109, VAL143, LEU159, SER160, TYR161, ALA162 and 3 more
- 4LM4 · Crystal structure of PDE10A2 with fragment ZT902 · JPZ A900 · binds TYR524, ASP674, LEU675, SER677, VAL678, ILE692, PHE696, GLN726 and 1 more
- 4PNN · Crystal structure of human tankyrase 2 in complex with 4HQN. · JPZ A1202 · binds PHE1030, HIS1031, GLY1032, TYR1060, PHE1061, ALA1062, LYS1067, SER1068 and 2 more
Residues it binds most
PHE 8, TYR 10, ALA 8, SER 10, LEU 4, GLU 6, GLY 6, HIS 6, LYS 6, VAL 4 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.