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Ligand · J5Z

J5Z · 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine

J5Z, 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine (C13 H10 F3 N5, 293.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
J5Z
Formula
C13 H10 F3 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

J5Z in 2 structures; the first of them:

  • 3I6R · Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based… · J5Z A1001 · binds LEU172, CYS175, LEU176, GLY181, CYS184, HIS185, PHE188, LEU197 and 8 more
  • 3I6R · Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based… · J5Z A1001 · binds LEU172, CYS175, LEU176, GLY181, CYS184, HIS185, PHE188, LEU197 and 8 more

Residues it binds most

LEU 2, CYS 2, GLY 2, PHE 2, ARG 2, HIS 2, ILE 2, MET 2, VAL 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • ORO · Orotic acid

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