GL1X · GenesisL1 explorer

Ligand · J4V

J4V · (1R,2r,3S,5R,7R)-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]tricyclo[3.3.1.1~3,7~]decane-2-carboxamide

J4V, (1R,2r,3S,5R,7R)-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]tricyclo[3.3.1.1~3,7~]decane-2-carboxamide (C25 H25 F3 N2 O3, 458.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2…

Component
J4V
Formula
C25 H25 F3 N2 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

J4V in 4 structures; the first of them:

  • 6EE3 · X-ray crystal structure of Pf-M1 in complex with inhibitor (6k) and catalytic zinc ion · J4V A1102 · binds LEU304, THR305, GLN317, GLU319, ALA320, ASN458, VAL459, GLY460 and 13 more
  • 6EEE · X-ray crystal structure of Pf-M17 in complex with inhibitor (6k) and regulatory zinc ion · J4V A1001 · binds LYS374, ASP379, LYS386, GLY390, SER391, MET392, LEU395, MET396 and 17 more
  • 6EE3 · X-ray crystal structure of pf-M1 in complex with inhibitor (6K) and catalytic zinc ion · J4V A1102 · binds LEU304, THR305, GLN317, GLU319, ALA320, ASN458, VAL459, GLY460 and 13 more
  • 6EEE · X-ray crystal structure of pf-M17 in complex with inhibitor (6K) and regulatory zinc ion · J4V A1001 · binds LYS374, ASP379, LYS386, GLY390, SER391, MET392, LEU395, MET396 and 17 more

Residues it binds most

GLY 26, ASP 24, LEU 26, MET 26, ALA 26, LYS 24, THR 26, PHE 24, SER 24, GLU 26 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • MG · Magnesium ion
  • CO3 · Carbonate ion
  • PO4 · Phosphate ion
  • SO4 · Sulfate ion
  • 1PE · Pentaethylene glycol
  • 2PE · Nonaethylene glycol
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.