Ligand · J11
J11 · N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine
J11, N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine (C21 H30 F N5, 371.5 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding…
- Component
- J11
- Formula
- C21 H30 F N5
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
J11 in 6 structures; the first of them:
- 3JWU · Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with… · J11 A800 · binds MET336, LEU337, GLN478, PRO565, VAL567, PHE584, SER585, GLY586 and 7 more
- 3JWY · Structure of endothelial nitric oxide synthase heme domain complexed with… · J11 A800 · binds VAL106, LEU107, GLN249, PRO336, VAL338, PHE355, SER356, GLY357 and 7 more
- 3JX4 · Structure of rat neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex… · J11 A800 · binds VAL336, LEU337, GLN478, PRO565, VAL567, PHE584, SER585, GLY586 and 7 more
- 3JWU · Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with… · J11 A800 · binds MET336, LEU337, GLN478, PRO565, VAL567, PHE584, SER585, GLY586 and 7 more
- 3JWY · Structure of endothelial nitric oxide synthase heme domain complexed with… · J11 A800 · binds VAL106, LEU107, GLN249, PRO336, VAL338, PHE355, SER356, GLY357 and 7 more
- 3JX4 · Structure of rat neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex… · J11 A800 · binds VAL336, LEU337, GLN478, PRO565, VAL567, PHE584, SER585, GLY586 and 7 more
Residues it binds most
TRP 12, TYR 12, VAL 12, MET 12, GLN 12, GLU 12, GLY 12, LEU 12, PHE 12, PRO 12 (residue and the binding sites it lines).
Found with
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