GL1X · GenesisL1 explorer

Ligand · IZB

IZB · N-[(1S)-1-(1H-benzimidazol-2-yl)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

IZB, N-[(1S)-1-(1H-benzimidazol-2-yl)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide (C27 H27 N5 O6 S2, 581.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
IZB
Formula
C27 H27 N5 O6 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IZB in 2 structures; the first of them:

  • 2CNH · Structural Insights into the Design of Nonpeptidic Isothiazolidi - Containing Inhibitors… · IZB A1300 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 8 more
  • 2CNH · Structural insights into the design of nonpeptidic isothiazolidinone- containing… · IZB A1300 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 8 more

Residues it binds most

GLY 2, ARG 2, ASP 2, GLN 2, ALA 2, CYS 2, ILE 2, PHE 2, SER 2, TYR 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion

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