Ligand · ITI
ITI · N-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide
ITI, N-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide (C33 H29 N7 O2 S, 587.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- ITI
- Formula
- C33 H29 N7 O2 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
ITI in 2 structures; the first of them:
- 3LZB · EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor · ITI A1 · binds LEU694, VAL702, ALA719, ILE720, LYS721, MET742, CYS751, ARG752 and 16 more
- 3LZB · EGFR kinase domain complexed with an IMIDAZO[2,1-B]THIAZOLE inhibitor · ITI A1 · binds LEU694, VAL702, ALA719, ILE720, LYS721, MET742, CYS751, ARG752 and 16 more
Residues it binds most
LEU 8, CYS 8, ILE 8, MET 8, PHE 8, THR 8, ASP 8, ARG 8, GLY 8, ALA 8 (residue and the binding sites it lines).
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