Ligand · IIB

IIB · 1-{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide

IIB, 1-{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide (C27 H28 Cl N5 O2 S, 522.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: IIB
Formula: C27 H28 Cl N5 O2 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

IIB in 2 structures; the first of them:

2BQ6 · Crystal structure of factor Xa in complex with 21 · IIB B1246 · binds LYS96, GLU97, THR98, TYR99, ARG143, GLU147, PHE174, ASP189 and 15 more
2BQ6 · Crystal structure of factor xa in complex with 21 · IIB B1246 · binds LYS96, GLU97, THR98, TYR99, ARG143, GLU147, PHE174, ASP189 and 15 more

Residues it binds most

GLU 2, GLY 2, ARG 2, CYS 2, SER 2, TYR 2, ALA 2, ASP 2, GLN 2, ILE 2 (residue and the binding sites it lines).

Found with

CA · Calcium ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.