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Ligand · IHZ

IHZ · 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide

IHZ, 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide (C21 H17 F3 N4 O2, 414.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
IHZ
Formula
C21 H17 F3 N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IHZ in 2 structures; the first of them:

  • 3DKO · Complex between the kinase domain of human ephrin type-a receptor 7 (epha7) and inhibitor… · IHZ A1001 · binds ILE639, VAL647, ALA663, LYS665, GLU682, ILE685, MET686, PHE689 and 14 more
  • 3DKO · Complex between the kinase domain of human ephrin type-a receptor 7 (EPHA7) and inhibitor… · IHZ A1001 · binds ILE639, VAL647, ALA663, LYS665, GLU682, ILE685, MET686, PHE689 and 14 more

Residues it binds most

VAL 2, ILE 2, PHE 2, GLU 2, MET 2, ALA 2, ASP 2, GLY 2, HIS 2, LEU 2 (residue and the binding sites it lines).

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