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Ligand · HS5

HS5 · 2-[(4-fluorophenyl)sulfonyl-(2-hydroxyethyl)amino]-N-oxo-ethanamide

HS5, 2-[(4-fluorophenyl)sulfonyl-(2-hydroxyethyl)amino]-N-oxo-ethanamide (C10 H11 F N2 O5 S, 290.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
HS5
Formula
C10 H11 F N2 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

HS5 in 2 structures; the first of them:

  • 3F18 · Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor… · HS5 A0 · binds GLY179, ILE180, LEU181, ALA182, HIS183, LEU214, THR215, HIS218 and 8 more
  • 3F18 · Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor… · HS5 A0 · binds GLY179, ILE180, LEU181, ALA182, HIS183, LEU214, THR215, HIS218 and 8 more

Residues it binds most

HIS 2, LEU 2, THR 2, ALA 2, GLU 2, GLY 2, ILE 2, PHE 2, PRO 2, TYR 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion

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