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Ligand · HR0

HR0 · 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile

HR0, 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile (C11 H7 N5 O, 225.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
HR0
Formula
C11 H7 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

HR0 in 2 structures; the first of them:

  • 7DYQ · Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor… · HR0 A401 · binds TYR181, PHE189, HIS192, GLU194, SER200, ASN202, LYS210, THR211 and 7 more
  • 7DYQ · Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor… · HR0 A401 · binds TYR181, PHE189, HIS192, GLU194, SER200, ASN202, LYS210, THR211 and 7 more

Residues it binds most

ALA 2, HIS 2, PHE 2, ASN 2, GLU 2, GLY 2, LYS 2, SER 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • FE · Fe (III) ion

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