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Ligand · HFQ

HFQ · 2,4-dihydroxyphenacyl coenzyme A

HFQ, 2,4-dihydroxyphenacyl coenzyme A (C29 H42 N7 O19 P3 S, 917.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
HFQ
Formula
C29 H42 N7 O19 P3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

HFQ in 4 structures; the first of them:

  • 4K49 · X-ray crystal structure of E. coli YdiI complexed with 2,4-dihydroxyphenacyl CoA · HFQ C201 · binds GLN48, PRO49, PHE50, LEU52, LEU53, HIS54, GLY55, GLY56 and 20 more
  • 4K4D · X-ray crystal structure of E. coli YbdB complexed with 2,4-dihydroxyphenacyl-CoA · HFQ A201 · binds GLN48, PRO49, LEU53, HIS54, GLY55, HIS89, HIS90, ARG91 and 11 more
  • 4K49 · X-ray crystal structure of E. COLI ydii complexed with 2,4- dihydroxyphenacyl CoA · HFQ C201 · binds GLN48, PRO49, PHE50, LEU52, LEU53, HIS54, GLY55, GLY56 and 20 more
  • 4K4D · X-ray crystal structure of E. COLI ybdb complexed with 2,4- dihydroxyphenacyl-CoA · HFQ A201 · binds GLN48, PRO49, LEU53, HIS54, GLY55, HIS89, HIS90, ARG91 and 11 more

Residues it binds most

HIS 12, LEU 12, VAL 12, GLY 12, SER 12, ARG 12, PRO 12, GLN 12, GLU 12, MET 10 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • MLI · Malonate ion

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