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Ligand · H1X

H1X · 2-[(5-tert-butyl-2-methyl-phenyl)sulfonylamino]benzoic acid

H1X, 2-[(5-tert-butyl-2-methyl-phenyl)sulfonylamino]benzoic acid (C18 H21 N O4 S, 347.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
H1X
Formula
C18 H21 N O4 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

H1X in 4 structures; the first of them:

  • 7DAX · Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase… · H1X A301 · binds ARG13, SER14, PRO15, LEU38, PHE39, PHE110, SER114, MET117 and 5 more
  • 7DAY · Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase… · H1X A301 · binds PRO15, LEU38, PHE39, GLN43, PHE110, ASP113, SER114, MET117 and 3 more
  • 7DAX · Crystal structure of drosophila melanogaster noppera-bo, glutathione S-transferase… · H1X A301 · binds ARG13, SER14, PRO15, LEU38, PHE39, PHE110, SER114, MET117 and 4 more
  • 7DAY · Crystal structure of drosophila melanogaster noppera-bo, glutathione S-transferase… · H1X A301 · binds PRO15, LEU38, PHE39, GLN43, PHE110, ASP113, SER114, MET117 and 3 more

Residues it binds most

SER 8, MET 12, LEU 9, PHE 8, ARG 10, GLU 4, TRP 4, PRO 7, GLN 6, THR 6 (residue and the binding sites it lines).

Found with

  • GSH · Glutathione
  • CL · Chloride ion
  • DMS · Dimethyl sulfoxide
  • DTT · 2,3-dihydroxy-1,4-dithiobutane

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