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Ligand · H0C

H0C · [(2~{R},3~{R},4~{R},5~{S},6~{S})-2-[[(1~{R},3~{S}, 5~{S},8~{R},9~{S},10~{R},11~{R},13~{R},14~{S},17~{R})-10-(hydroxymethyl)-13-methyl-1,5,11,14-tetrakis(oxidanyl)-17-(5-oxidanylidene-2~{H}-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl]oxy]-6-methyl-3,5-bis(oxidanyl)oxan-4-yl] anthracene-9-carboxylate

H0C, [(2~{R},3~{R},4~{R},5~{S},6~{S})-2-[[(1~{R},3~{S}, 5~{S},8~{R},9~{S},10~{R},11~{R},13~{R},14~{S},17~{R})-10-(hydroxymethyl)-13-methyl-1,5,11,14-tetrakis(oxidanyl)-17-(5-oxidanylidene-2~{H}-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodec…

Component
H0C
Formula
C44 H52 O13
Class
ligand
Structures
4
PDB entries
2

Binding sites

H0C in 4 structures; the first of them:

  • 7D92 · Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and… · H0C A1121 · binds GLN111, THR114, GLU115, GLN119, ASP121, ASN122, LEU125, TYR308 and 12 more
  • 7D93 · Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and… · H0C A1121 · binds GLN111, GLU115, GLU116, GLU117, GLN119, ASP121, ASN122, LEU125 and 15 more
  • 7D92 · Crystal structure of the NA+,K+-ATPase in the E2P state with bound MG2+ and… · H0C A1121 · binds GLN111, THR114, GLU115, GLN119, ASN122, LEU125, TYR308, GLU312 and 10 more
  • 7D93 · Crystal structure of the NA+,K+-ATPase in the E2P state with bound MG2+ and… · H0C A1121 · binds GLN111, GLU115, GLU117, GLN119, ASN122, LEU125, TYR308, GLU312 and 10 more

Residues it binds most

PHE 6, GLU 6, GLN 6, ASP 6, LEU 6, ILE 6, THR 6, ARG 6, ALA 6, ASN 6 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine
  • MG · Magnesium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • NA · Sodium ion

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