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Ligand · GNX

GNX · 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose

GNX, 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (C6 H13 N O11 S2, 339.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
GNX
Formula
C6 H13 N O11 S2
Class
sugar
Structures
4
PDB entries
2

Binding sites

GNX in 4 structures; the first of them:

  • 3UD8 · Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex · GNX D2 · binds ASN18, LEU111, LYS112, LYS113, LYS118, ARG122, GLN127, ALA129
  • 4OEE · Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex · GNX B2 · binds ASN27, LEU118, LYS119, ARG120, LYS125, ALA136
  • 3UD8 · Crystal structure analysis of FGF1-DISACCHARIDE(NI22) complex · GNX D2 · binds ASN18, LEU111, LYS112, LYS113, LYS118, ARG122, GLN127, ALA129
  • 4OEE · Crystal structure analysis of FGF2-disaccharide (S3I2) complex · GNX B2 · binds ASN27, LEU118, LYS119, ARG120, LYS125, ALA136

Residues it binds most

LYS 4, ALA 4, ARG 4, ASN 4, LEU 4, GLN 2 (residue and the binding sites it lines).

Found with

  • IDY · 1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid
  • PO4 · Phosphate ion

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