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Ligand · GIQ

GIQ · 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine

GIQ, 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine (C11 H10 N4, 198.2 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
GIQ
Formula
C11 H10 N4
Class
ligand
Structures
7
PDB entries
4

Binding sites

GIQ in 7 structures; the first of them:

  • 2HKC · NMR Structure of the IQ-modified Dodecamer CTCGGC[IQ]GCCATC · GIQ A25 · binds DG7, DC8, DG17, DC18, DG19
  • 2Z2G · NMR Structure of the IQ-modified Dodecamer CTC[IQ]GGCGCCATC · GIQ A25 · binds DG4, DG5, DC20, DC21, DG22
  • 2Z2H · NMR Structure of the IQ-modified Dodecamer CTCG[IQ]GCGCCATC · GIQ A25 · binds DG4, DG5, DC6, DG19, DC20, DC21
  • 5SG2 · CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH… · GIQ A803 · binds TYR524, LEU635, LEU675, SER677, VAL678, ILE692, PHE696, MET713 and 2 more
  • 2HKC · NMR structure of the iq-modified dodecamer CTCGGC[IQ]GCCATC · GIQ A25 · binds DG7, DC8, DG17, DC18, DG19
  • 2Z2G · NMR structure of the iq-modified dodecamer CTC[IQ]GGCGCCATC · GIQ A25 · binds DG4, DG5, DC20, DC21, DG22
  • 2Z2H · NMR structure of the iq-modified dodecamer CTCG[IQ]GCGCCATC · GIQ A25 · binds DG4, DG5, DC6, DG19, DC20, DC21

Residues it binds most

DG 6, DC 6, LEU 2, PHE 2, GLN 2, ILE 2, MET 2, SER 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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