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Ligand · GIL

GIL · 2-{[6-{3-[amino(imino)methyl]phenoxy}-4-(diisopropylamino)-3,5-difluoropyridin-2-yl]oxy}-5-[(isobutylamino)carbonyl]ben zoic acid

GIL, 2-{[6-{3-[amino(imino)methyl]phenoxy}-4-(diisopropylamino)-3,5-difluoropyridin-2-yl]oxy}-5-[(isobutylamino)carbonyl]ben zoic acid (C30 H35 F2 N5 O5, 583.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
GIL
Formula
C30 H35 F2 N5 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

GIL in 2 structures; the first of them:

  • 2C4F · crystal structure of factor VII.stf complexed with pd0297121 · GIL H302 · binds GLN40, HIS57, GLY97, THR98, THR99, GLN143, THR151, PRO170I and 13 more
  • 2C4F · Crystal structure of factor VII.STF complexed with PD0297121 · GIL H302 · binds GLN40, HIS57, GLY97, THR98, THR99, GLN143, THR151, PRO170I and 13 more

Residues it binds most

GLY 2, SER 2, THR 2, CYS 2, GLN 2, ASP 2, HIS 2, LYS 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • FUC · alpha-L-fucopyranose
  • GLC · alpha-D-glucopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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