Ligand · GHW
GHW · N-({4-[(2-amino-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)sulfanyl]phenyl}carbonyl)-L-glutamic acid
GHW, N-({4-[(2-amino-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)sulfanyl]phenyl}carbonyl)-L-glutamic acid (C19 H18 N4 O6 S2, 462.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding…
- Component
- GHW
- Formula
- C19 H18 N4 O6 S2
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
GHW in 4 structures; the first of them:
- 3GHW · Human dihydrofolate reductase inhibitor complex · GHW A187 · binds ILE7, VAL8, ALA9, LEU22, ARG28, GLU30, PHE31, ARG32 and 11 more
- 3GI2 · Human dihydrofolate reductase Q35K mutant inhibitor complex · GHW A187 · binds ILE7, VAL8, ALA9, LEU22, GLU30, PHE31, ARG32, PHE34 and 11 more
- 3GHW · Human dihydrofolate reductase inhibitor complex · GHW A187 · binds ILE7, VAL8, ALA9, LEU22, ARG28, GLU30, PHE31, ARG32 and 11 more
- 3GI2 · Human dihydrofolate reductase Q35K mutant inhibitor complex · GHW A187 · binds ILE7, VAL8, ALA9, LEU22, GLU30, PHE31, ARG32, PHE34 and 11 more
Residues it binds most
ARG 4, ILE 4, LEU 4, PHE 4, THR 4, VAL 4, ALA 4, ASN 4, GLU 4, LYS 2 (residue and the binding sites it lines).
Found with
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