Ligand · GGF
GGF · 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R}, 17~{R},18~{R})-17-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3, 12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$L^{5}, 12$L^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]-1~{H}-purin-6-one
GGF, 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R}, 17~{R},18~{R})-17-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3, 12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$L^{5}…
- Component
- GGF
- Formula
- C20 H22 F2 N10 O12 P2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
GGF in 2 structures; the first of them:
- 6YDB · Human wtSTING in complex with 2',2'-difluoro-3',3'-c-di-GMP · GGF A401 · binds SER162, TYR163, GLY166, TYR167, ILE235, ARG238, VAL239, TYR240 and 6 more
- 6YDB · Human wtsting in complex with 2',2'-difluoro-3',3'-C-di-gmp · GGF A401 · binds SER162, TYR163, GLY166, TYR167, ILE235, ARG238, VAL239, TYR240 and 5 more
Residues it binds most
TYR 2, SER 2, THR 2, ARG 2, GLU 2, GLY 2, ILE 2, PRO 2, VAL 2, ASN 1 (residue and the binding sites it lines).
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