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Ligand · GBZ

GBZ · (2~{S})-2-[[(2~{S})-6-[2-[(6-fluoranylpyridin-3-yl)carbonylamino]ethyl-phenyl-amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid

GBZ, (2~{S})-2-[[(2~{S})-6-[2-[(6-fluoranylpyridin-3-yl)carbonylamino]ethyl-phenyl-amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid (C26 H30 F N5 O9, 575.5 g/mol), in the MolNFT structures on GenesisL1…

Component
GBZ
Formula
C26 H30 F N5 O9
Class
ligand
Structures
2
PDB entries
1

Binding sites

GBZ in 2 structures; the first of them:

  • 6HKZ · X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a… · GBZ A818 · binds GLY206, LYS207, VAL208, PHE209, ARG210, TYR234, ASN257, ASP387 and 21 more
  • 6HKZ · X-ray structure of human glutamate carboxypeptidase II (gcpii) in complex with a… · GBZ A818 · binds GLY206, LYS207, VAL208, PHE209, ARG210, TYR234, ASN257, ASP387 and 21 more

Residues it binds most

ARG 2, GLY 2, ASP 2, GLU 2, LYS 2, TYR 2, ASN 2, PHE 2, SER 2, HIS 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • EDO · 1,2-ethanediol

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