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Ligand · FYC

FYC · 3-(2-fluorophenyl)-2-methyl-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)acrylamide

FYC, 3-(2-fluorophenyl)-2-methyl-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)acrylamide (C18 H16 F N3 O2, 325.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
FYC
Formula
C18 H16 F N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FYC in 2 structures; the first of them:

  • 5AE2 · Ether Lipid-Generating Enzyme AGPS in complex with inhibitor 1e · FYC A888 · binds VAL241, ASP303, ILE511, ALA512, MET514, ARG515, ILE524, GLY525 and 8 more
  • 5AE2 · Ether lipid-generating enzyme agps in complex with inhibitor 1E · FYC A888 · binds VAL241, ASP303, ILE511, ALA512, MET514, ARG515, ILE524, GLY525 and 8 more

Residues it binds most

ALA 8, HIS 8, TYR 8, ILE 8, ARG 8, ASP 8, GLU 8, GLY 8, MET 8, PHE 8 (residue and the binding sites it lines).

Found with

  • FAD · Flavin-adenine dinucleotide
  • SO4 · Sulfate ion

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