Ligand · FWX

FWX · 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7, 8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide

FWX, 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7, 8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide (C22 H29 N5 O2, 395.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component: FWX
Formula: C22 H29 N5 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

FWX in 2 structures; the first of them:

7CFM · Cryo-EM structure of the P395-bound GPBAR-Gs complex · FWX R401 · binds LEU71, LEU74, TRP75, TYR89, PRO92, ASN93, PHE96, LEU97 and 10 more
7CFM · Cryo-EM structure of the P395-bound gpbar-gs complex · FWX R401 · binds LEU71, LEU74, TRP75, TYR89, PRO92, PHE96, SER157, PHE161 and 7 more

Residues it binds most

LEU 2, SER 2, TYR 2, PHE 2, GLU 2, PRO 2, TRP 2, ASN 1 (residue and the binding sites it lines).

Found with

CLR · Cholesterol

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