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Ligand · FVW

FVW · (2~{S})-2-[[(2~{S})-6-[(6-fluoranylpyridin-3-yl)-methyl-amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid

FVW, (2~{S})-2-[[(2~{S})-6-[(6-fluoranylpyridin-3-yl)-methyl-amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid (C18 H23 F N4 O8, 442.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
FVW
Formula
C18 H23 F N4 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

FVW in 2 structures; the first of them:

  • 6H7Z · X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a… · FVW A832 · binds GLY206, LYS207, VAL208, PHE209, ARG210, TYR234, GLY256, ASN257 and 19 more
  • 6H7Z · X-ray structure of human glutamate carboxypeptidase II (gcpii) in complex with a… · FVW A832 · binds GLY206, LYS207, VAL208, PHE209, ARG210, TYR234, GLY256, ASN257 and 19 more

Residues it binds most

GLY 2, ARG 2, GLU 2, TYR 2, ASN 2, ASP 2, LYS 2, HIS 2, LEU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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