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Ligand · FUG

FUG · Fumagillin

FUG, Fumagillin (C26 H36 O7, 460.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
FUG
Formula
C26 H36 O7
Class
ligand
Structures
4
PDB entries
2

Binding sites

FUG in 4 structures; the first of them:

  • 1BOA · Human methionine aminopeptidase 2 complexed with angiogenesis inhibitor fumagillin · FUG A480 · binds PHE219, ALA230, HIS231, ASP262, ASN327, LEU328, ASN329, GLY330 and 13 more
  • 3FMQ · Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with… · FUG A481 · binds PHE97, PRO98, ALA108, HIS109, ASP206, LEU207, HIS208, HIS210 and 8 more
  • 1BOA · Human methionine aminopeptidase 2 complexed with angiogenesis inhibitor fumagillin · FUG A480 · binds PHE219, ALA230, HIS231, ASP262, ASN327, LEU328, ASN329, GLY330 and 13 more
  • 3FMQ · Crystal structure of an encephalitozoon cuniculi methionine aminopeptidase type 2 with… · FUG A481 · binds PHE97, PRO98, ALA108, HIS109, ASP206, LEU207, HIS208, HIS210 and 8 more

Residues it binds most

HIS 6, LEU 6, ALA 6, ASP 6, PHE 6, GLU 6, ILE 6, PRO 4, TYR 6, VAL 6 (residue and the binding sites it lines).

Found with

  • CO · Cobalt (II) ion
  • FE · Fe (III) ion
  • SO4 · Sulfate ion

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