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Ligand · FTL

FTL · 4-[(3-cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-2-naphthalen-1-yl-benzonitrile

FTL, 4-[(3-cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-2-naphthalen-1-yl-benzonitrile (C30 H23 N5, 453.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within…

Component
FTL
Formula
C30 H23 N5
Class
ligand
Structures
1
PDB entries
1

Binding sites

FTL in 1 structure; the first of them:

  • 1NL4 · Crystal Structure of Rat Farnesyl Transferase in Complex With A Potent Biphenyl Inhibitor · FTL B1 · binds TYR166, TYR93, LEU96, SER99, TRP102, TRP106, ARG202, ASP297 and 7 more

Residues it binds most

ASP 1, TRP 1, TYR 1, ARG 1, CYS 1, HIS 1, LEU 1, PHE 1, SER 1 (residue and the binding sites it lines).

Found with

  • HFP · Alpha-hydroxyfarnesylphosphonic acid
  • ZN · Zinc ion

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