Ligand · FTI
FTI · 1-{2-[3-(4-cyano-benzyl)-3H-imidazol-4-yl]-acetyl}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile
FTI, 1-{2-[3-(4-cyano-benzyl)-3H-imidazol-4-yl]-acetyl}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile (C29 H23 N5 O, 457.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…
- Component
- FTI
- Formula
- C29 H23 N5 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
FTI in 2 structures; the first of them:
- 1N9A · Farnesyltransferase complex with tetrahydropyridine inhibitors · FTI B1 · binds TYR166, LEU96, SER99, TRP102, TRP106, ARG202, ASP297, ASP359 and 1 more
- 1N9A · Farnesyltransferase complex with tetrahydropyridine inhibitors · FTI B1 · binds TYR166, LEU96, SER99, TRP102, TRP106, ARG202, ASP297, ASP359 and 1 more
Residues it binds most
ASP 2, TRP 2, TYR 2, ARG 2, LEU 2, SER 2 (residue and the binding sites it lines).
Found with
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