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Ligand · FPF

FPF · (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate

FPF, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate (C15 H27 F O7 P2, 400.3 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within…

Component
FPF
Formula
C15 H27 F O7 P2
Class
ligand
Structures
3
PDB entries
3

Binding sites

FPF in 3 structures; the first of them:

  • 7XQZ · Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with… · FPF A601 · binds ARG132, LYS133, GLN163, TRP165, PHE248, ILE249, MET252, PHE293 and 11 more
  • 9C7J · Crystal structure of caryolan-1-ol synthase complexed with 2-fluorofarnesyl diphosphate · FPF A401 · binds TRP56, TRP75, LEU76, ALA79, PHE80, ASP83, ASP87, PHE141 and 12 more
  • 9C7L · Crystal structure of pentalenene synthase variant F76A complexed with 2-fluorofarnesyl… · FPF A401 · binds LEU53, PHE57, MET73, ALA76, PHE77, ASP80, TYR146, TYR150 and 13 more

Residues it binds most

PHE 6, TRP 6, ASP 6, ALA 6, LEU 5, ARG 6, TYR 6, THR 6, ASN 5, SER 5 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • DPO · Diphosphate
  • PO4 · Phosphate ion

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