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Ligand · FNF

FNF · (2R,3R,4S,5R,6R)-4-(formylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)

FNF, (2R,3R,4S,5R,6R)-4-(formylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) (C17 H27…

Component
FNF
Formula
C17 H27 N3 O15 P2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FNF in 2 structures; the first of them:

  • 4LXX · Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Fuc3NFo… · FNF A304 · binds LYS9, ASN35, GLU77, PHE78, ASP79, ASN94, ILE95, HIS96 and 13 more
  • 4LXX · Crystal structure wlard, a sugar 3N-formyl transferase in the presence of dtdp-FUC3NFO… · FNF A304 · binds LYS9, ASN35, GLU77, PHE78, ASP79, ASN94, ILE95, HIS96 and 13 more

Residues it binds most

PHE 4, ASN 4, ASP 4, ILE 4, TYR 4, ARG 4, GLN 4, GLU 4, GLY 4, HIS 4 (residue and the binding sites it lines).

Found with

  • FON · N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid
  • CL · Chloride ion
  • EDO · 1,2-ethanediol
  • MPO · 3[N-morpholino]propane sulfonic acid

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