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Ligand · FM6

FM6 · [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl(phenylcarbonyl)amino]propyl]phosphonic acid

FM6, [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl(phenylcarbonyl)amino]propyl]phosphonic acid (C16 H16 Cl2 N O5 P, 404.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
FM6
Formula
C16 H16 Cl2 N O5 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

FM6 in 4 structures; the first of them:

  • 3ZHX · Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue · FM6 A501 · binds ASP151, SER152, GLU153, THR175, ALA176, SER177, SER213, ASN218 and 5 more
  • 3ZHY · Structure of Mycobacterium tuberculosis DXR in complex with a di- substituted… · FM6 A501 · binds LYS128, ASP151, SER152, GLU153, THR175, ALA176, SER177, GLY178 and 10 more
  • 3ZHX · Structure of mycobacterium tuberculosis dxr in complex with a fosmidomycin analogue · FM6 A501 · binds ASP151, SER152, GLU153, THR175, ALA176, SER177, SER213, ASN218 and 5 more
  • 3ZHY · Structure of mycobacterium tuberculosis dxr in complex with a di- substituted… · FM6 A501 · binds LYS128, ASP151, SER152, GLU153, THR175, ALA176, SER177, GLY178 and 10 more

Residues it binds most

SER 6, GLU 6, LYS 6, ASN 6, GLY 4, MET 6, ALA 6, ASP 6, PRO 6, THR 6 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate

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