Ligand · FAP
FAP · (2S)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol
FAP, (2S)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol (C21 H23 F2 N5 O2, 415.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…
- Component
- FAP
- Formula
- C21 H23 F2 N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
FAP in 2 structures; the first of them:
- 1H00 · CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor · FAP A1300 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 11 more
- 1H00 · CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor · FAP A1300 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 11 more
Residues it binds most
ALA 2, ASP 2, GLN 2, GLU 2, LEU 2, LYS 2, PHE 2, VAL 2, ASN 2, HIS 2 (residue and the binding sites it lines).
Found with
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