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Ligand · F5U

F5U · 2-(5-methoxy-1H-indol-3-yl)ethanamine

F5U, 2-(5-methoxy-1H-indol-3-yl)ethanamine (C11 H14 N2 O, 190.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
F5U
Formula
C11 H14 N2 O
Class
ligand
Structures
6
PDB entries
4

Binding sites

F5U in 6 structures; the first of them:

  • 7BS4 · Bovine Pancreatic Trypsin with 5-Methoxytryptamine (Cryo) · F5U A302 · binds HIS63, ASP194, SER195, CYS196, GLN197, SER200, VAL214, SER215 and 5 more
  • 7DAK · The crystal structure of a serotonin N-acetyltransferase in complex with… · F5U B401 · binds TRP133, TRP188, ASP189, PHE224, ASP226, PHE249, ASN184, ASN220 and 1 more
  • 7BRX · Bovine pancreatic trypsin with 5-methoxytryptamine (room temperature) · F5U A302 · binds ASP194, SER195, GLN197, SER200, SER215, TRP216, GLY217, GLY219 and 2 more
  • 7BS4 · Bovine pancreatic trypsin with 5-methoxytryptamine (cryo) · F5U A302 · binds ASP194, SER195, CYS196, GLN197, SER200, SER215, TRP216, GLY217 and 2 more
  • 7DAK · The crystal structure of a serotonin N-acetyltransferase in complex with… · F5U B401 · binds TRP188, ASP226, ASN184, ASN220, ILE245
  • 7WB8 · Crystal structure of bovine pancreatic trypsin in complex with 5- methoxytryptamine at… · F5U A301 · binds HIS63, ASP194, SER195, CYS196, GLN197, SER200, VAL214, SER215 and 5 more

Residues it binds most

SER 5, CYS 6, GLY 4, ASP 8, TRP 8, PHE 5, ASN 3, GLN 4, HIS 4, ILE 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • DMS · Dimethyl sulfoxide
  • ACO · Acetyl coenzyme *A

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