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Ligand · F51

F51 · 2-([1,1'-biphenyl]-4-yl)-3-methyl-1,7-naphthyridine-4-carboxylic acid

F51, 2-([1,1'-biphenyl]-4-yl)-3-methyl-1,7-naphthyridine-4-carboxylic acid (C22 H16 N2 O2, 340.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
F51
Formula
C22 H16 N2 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

F51 in 1 structure; the first of them:

  • 6CJG · Human dihydroorotate dehydrogenase bound to napthyridine inhibitor 46 · F51 A503 · binds TYR38, MET43, GLN47, PRO52, ALA55, HIS56, ALA59, PHE62 and 6 more

Residues it binds most

ALA 1, LEU 1, PRO 1, TYR 1, ARG 1, GLN 1, HIS 1, MET 1, PHE 1, THR 1 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • ORO · Orotic acid
  • ZWI · 3-[decyl(dimethyl)ammonio]propane-1-sulfonate
  • SO4 · Sulfate ion
  • GOL · Glycerol

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