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Ligand · F1U

F1U · (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl) cyclohexan-1-ol

F1U, (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl) cyclohexan-1-ol (C16 H25 N O2, 263.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
F1U
Formula
C16 H25 N O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

F1U in 1 structure; the first of them:

  • 6M47 · X-ray structure of a Drosophila dopamine transporter with NET-like mutations… · F1U A608 · binds PHE43, ALA44, ASP46, ALA117, VAL120, TYR123, TYR124, PHE319 and 5 more
  • 6M47 · X-ray structure of a drosophila dopamine transporter with net-like mutations… · F1U A608 · binds PHE43, ASP46, ALA117, TYR124, PHE319, PHE325, SER421, GLY425

Residues it binds most

PHE 2, ALA 2, SER 2, TYR 2, ASP 2, GLY 2, VAL 1 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • D10 · Decane
  • Y01 · Cholesterol hemisuccinate
  • NA · Sodium ion
  • GLC · alpha-D-glucopyranose
  • CL · Chloride ion

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