Ligand · F0U

F0U · 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide

F0U, 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide (C18 H14 Br Cl2 N5 O2, 483.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every…

Component: F0U
Formula: C18 H14 Br Cl2 N5 O2
Class: ligand
Structures: 2
PDB entries: 2

Binding sites

F0U in 2 structures; the first of them:

6M2W · Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) · F0U A5105 · binds UNK4319, TYR4560, ARG4563, PHE4564, ALA4566, LEU4567, CYS4657, TYR4791 and 7 more
7CF9 · Structure of RyR1 (Ca2+/CHL) · F0U A5203 · binds UNK4319, TYR4560, ARG4563, PHE4564, LEU4567, CYS4657, TYR4791, LEU4792 and 6 more

Residues it binds most

TYR 8, LEU 8, ARG 8, ASP 8, CYS 8, GLY 8, ILE 8, MET 8, PHE 8, UNK 8 (residue and the binding sites it lines).

Found with

CA · Calcium ion
ZN · Zinc ion
ATP · Adenosine-5'-triphosphate
CFF · Caffeine

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