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Ligand · F0F

F0F · (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide

F0F, (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide (C15 H22 N2 O, 246.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
F0F
Formula
C15 H22 N2 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

F0F in 2 structures; the first of them:

  • 6M3Z · X-ray structure of a Drosophila dopamine transporter with NET-like mutations… · F0F A701 · binds PHE43, ALA44, ASP46, ALA117, VAL120, TYR123, TYR124, PHE319 and 7 more
  • 6M3Z · X-ray structure of a drosophila dopamine transporter with net-like mutations… · F0F A701 · binds PHE43, ALA44, ASP46, VAL120, TYR123, TYR124, PHE319, SER320 and 4 more

Residues it binds most

PHE 2, SER 2, GLY 2, TYR 2, ALA 2, ASP 2, VAL 2, LEU 1 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • D10 · Decane
  • Y01 · Cholesterol hemisuccinate
  • NA · Sodium ion
  • GLC · alpha-D-glucopyranose
  • CL · Chloride ion
  • GOL · Glycerol

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