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Ligand · EZI

EZI · 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile

EZI, 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile (C18 H15 N3 O2, 305.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
EZI
Formula
C18 H15 N3 O2
Class
ligand
Structures
2
PDB entries
2

Binding sites

EZI in 2 structures; the first of them:

  • 8JQR · Structure of human TRPV1 in complex with antagonist · EZI A1201 · binds TYR511, SER512, LEU515, LEU547, THR550, ASN551, LEU553, TYR554 and 9 more
  • 8X94 · Structure of human TRPV1 in complex with antagonist --protein purified without CHS · EZI A1201 · binds TYR511, SER512, LEU515, THR550, ASN551, LEU553, TYR554, THR556 and 8 more

Residues it binds most

LEU 8, THR 8, TYR 8, ALA 8, ARG 8, ASN 8, GLN 8, GLU 8, GLY 8, ILE 8 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol

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