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Ligand · EZ8

EZ8 · [1-[(2~{S},3~{S},4~{R},5~{S},6~{R})-2-[(1~{S},2~{S}, 4~{S},5~{S})-2-(2-chloroethyloxy)-4,5-bis[[4-(hydroxymethyl)phenyl]methylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-1,2,3-triazol-4-yl]methylazanium

EZ8, [1-[(2~{S},3~{S},4~{R},5~{S},6~{R})-2-[(1~{S},2~{S}, 4~{S},5~{S})-2-(2-chloroethyloxy)-4,5-bis[[4-(hydroxymethyl)phenyl]methylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-1,2,3-triazol-4-yl]methylazanium (C35…

Component
EZ8
Formula
C35 H48 Cl N6 O10 +1
Class
ligand
Structures
2
PDB entries
1

Binding sites

EZ8 in 2 structures; the first of them:

  • 6GHV · Structure of a DC-SIGN CRD in complex with high affinity glycomimetic. · EZ8 A1001 · binds PHE313, GLU347, ASN349, VAL351, GLY352, GLU354, GLU358, SER360 and 16 more
  • 6GHV · Structure of a dc-sign crd in complex with high affinity glycomimetic. · EZ8 A1001 · binds PHE313, GLU347, ASN349, VAL351, GLY352, GLU354, GLU358, SER360 and 13 more

Residues it binds most

ASN 12, SER 12, PHE 12, GLU 12, ARG 12, ASP 12, LYS 12, GLY 12, GLN 11, THR 12 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • CL · Chloride ion

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