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Ligand · ERD

ERD · (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one

ERD, (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one (C15 H12 O6, 288.3 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
ERD
Formula
C15 H12 O6
Class
ligand
Structures
5
PDB entries
3

Binding sites

ERD in 5 structures; the first of them:

  • 2NNL · Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the… · ERD D1331 · binds MET88, PHE90, SER128, ALA129, GLY130, ASN133, ILE134, TYR163 and 11 more
  • 7YJB · Crystal structure of Stenoloma chusanum chalcone synthase 1 (ScCHS1) complex with CoA and… · ERD A501 · binds THR136, SER137, GLY167, CYS168, GLU196, ILE197, THR198, ILE200 and 15 more
  • 8B3C · Chalcone synthase from Hordeum vulgare complexed with CoA and eriodictyol · ERD A401 · binds THR134, SER135, GLY165, CYS166, GLU194, ILE195, THR196, ALA199 and 15 more
  • 2NNL · Binding of two substrate analogue molecules to dihydroflavonol-4- reductase alters the… · ERD D1331 · binds MET88, PHE90, SER128, ALA129, GLY130, ASN133, ILE134, TYR163 and 11 more
  • 7YJB · Crystal structure of stenoloma chusanum chalcone synthase 1 (SCCHS1) complex with CoA and… · ERD A501 · binds THR136, SER137, GLY167, CYS168, GLU196, ILE197, THR198, ILE200 and 15 more

Residues it binds most

THR 8, GLY 8, ILE 8, PHE 8, SER 8, PRO 8, MET 8, ASN 8, ASP 4, LEU 8 (residue and the binding sites it lines).

Found with

  • COA · Coenzyme A
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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