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Ligand · ENL

ENL · (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

ENL, (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid (C8 H10 O5, 186.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
ENL
Formula
C8 H10 O5
Class
ligand
Structures
6
PDB entries
3

Binding sites

ENL in 6 structures; the first of them:

  • 3H61 · Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 5 more
  • 3H64 · Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 5 more
  • 3H69 · Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Zn2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 3 more
  • 3H61 · Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 5 more
  • 3H64 · Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 5 more
  • 3H69 · Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two ZN2+ atoms… · ENL A0 · binds ASP242, HIS244, ASP271, ARG275, ASN303, HIS304, HIS352, ARG400 and 3 more

Residues it binds most

HIS 12, ARG 12, ASP 12, ASN 12, PHE 12, TYR 12, GLU 10, VAL 10 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • ZN · Zinc ion

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