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Ligand · EAL

EAL · 1-((2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl)-L-proline

EAL, 1-((2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl)-L-proline (C18 H24 N2 O5, 348.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
EAL
Formula
C18 H24 N2 O5
Class
ligand
Structures
4
PDB entries
2

Binding sites

EAL in 4 structures; the first of them:

  • 1UZE · Complex of the anti-hypertensive drug enalaprilat and the human testicular angiotensin… · EAL A3002 · binds GLN281, HIS353, ALA354, SER355, VAL380, HIS383, GLU384, HIS387 and 8 more
  • 2X90 · Crystal structure of AnCE-enalaprilat complex · EAL A1617 · binds GLN265, HIS337, ALA338, SER339, THR364, HIS367, GLU368, HIS371 and 10 more
  • 1UZE · Complex of the anti-hypertensive drug enalaprilat and the human testicular angiotensin… · EAL A3002 · binds GLN281, HIS353, ALA354, SER355, VAL380, HIS383, GLU384, HIS387 and 8 more
  • 2X90 · Crystal structure of ance-enalaprilat complex · EAL A1617 · binds GLN265, HIS337, ALA338, SER339, THR364, HIS367, GLU368, HIS371 and 10 more

Residues it binds most

HIS 4, TYR 4, GLU 4, PHE 4, VAL 4, ALA 4, GLN 4, LYS 4, SER 4, ARG 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GLY · Glycine
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid

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